Titulo de la pagina
Design and management of selection and conservation programmes

Our research is focused on optimising the design and the management of genetic improvement and conservation programmes for farmed animals, including aquaculture species. Using computer simulations and analysis of genomic data, we evaluate new methods of selection and inbreeding control.

Grupo de investigación dependiente del

Animal Genetics Departament

In a selection programme, the objective is to maximise the genetic progress of economically important traits, but imposing restrictions on the rate at which inbreeding increases. The control of inbreeding is necessary to avoid or alleviate the reduction in viability and fertility (a phenomenon known as inbreeding depression), which may eventually make genetic progress impossible despite the presence of genetic variance for traits under selection.

In a conservation program focused on threatened populations, the objectives are to maximize genetic variability and control inbreeding for alleviating inbreeding depression.

Both genetic selection and inbreeding control can greatly benefit from the use of genomic tools.

The main objective of our group is to develop methodologies for optimizing the design and management of selection and conservation programmes in farmed animals, using currently available genomic tools.

In recent years we have developed an important activity in genetic improvement programmes of aquaculture species. Furthermore, our group is a pioneer in the use of technologies to guarantee the maintenance and sustainable use of threatened populations.

Our group carries out research projects on a variety of terrestrial (cattle, sheep and pigs) and aquatic (Atlantic salmon, turbot, seabream, seabass, common carp, rainbow trout and shrimp) species. Our research is based on analyses of empirical data and computer simulations.

In particular, we are interested in:

Genetic diversity within and between populations.

Determination of population structure.
Estimation of genomic coancestry between individuals.
Estimation of genomic inbreeding.
Estimation of current and historical effective population size.

Detection of genomic regions controlling traits of interest

Resistance to diseases, sexual determination, growth.

Optimisation of the design of genetic improvement programmes.

Creation of base populations

New breeding objectives (disease resistance, feed efficiency, fillet yield, product uniformity).
Prediction of genetic gain and inbreeding with different selection methods.

Genomic selection

Prediction of genetic gain and inbreeding with different mating systems.

Methods to maximise genetic gain while restricting the rate of inbreeding.
Development of strategies to control inbreeding and loss of genetic variability.

Optimisation of contributions using genomic relationship matrices.

Miembros

Design and management of selection and conservation programmes Members

Reinoso-Peláez E.L; Saura M; González-Recio Ó; González C; Fernández A; Peiro-Pastor R; López-García A; Saborío-Montero A; Calvo J.H; Ramón M; Serrano M; (2023)
Impact of oestrus synchronization devices on ewes vaginal microbiota and artificial insemination outcome
Frontiers in Microbiology | 14
DOI: 10.3389/fmicb.2023.1063807
Shin H.S.; Montachana Chimborazo M.E.; Escobar Rivas J.M.; Lorenzo-Felipe Á.; Martínez Soler M.; Zamorano Serrano M.J.; Fernández Martín J.; Ramírez Artiles J.S.; Peñate Sánchez A.; Lorenzo Navarro J.; Intriago Díaz W.; Torres R.; Reyes Abad E.; Afonso López J.M; (2023)
Genetic parameters for growth and morphological traits of the Pacific white shrimp Penaeus vannamei from a selective breeding programme in the industrial sector of Ecuador
Aquaculture Reports
DOI: 10.1016/j.aqrep.2023.101649
Morales-González E.; Villanueva B.; Toro M.Á.; Fernández J; (2023)
Maintenance of genetic diversity in subdivided populations using genomic coancestry matrices
Molecular Ecology Resources
DOI: 10.1111/1755-0998.13781
Bartolomé E; Valera M; Fernández J; Rodríguez-Ramilo S.T; (2022)
Effects of Selection on Breed Contribution in the Caballo de Deporte Español
Animals
DOI: 10.3390/ani12131635
Villanueva B; Fernández A; Peiró-Pastor R; Peñaloza C; Houston R.D; Sonesson A.K; Tsigenopoulos C.S; Bargelloni L; Gamsız K; Karahan B; Gökçek E.Ö; Fernández J; Saura M; (2022)
Population structure and genetic variability in wild and farmed Mediterranean populations of gilthead seabream and European seabass inferred from a 60K combined species SNP array
Aquaculture Reports
DOI: 10.1016/j.aqrep.2022.101145
García-Ballesteros S; Fernández J; Kause A; Villanueva B; (2022)
Predicted genetic gain for carcass yield in rainbow trout from indirect and genomic selection
Aquaculture
DOI: 10.1016/j.aquaculture.2022.738119
Canive M; Badia-Bringué G; Vázquez P; Garrido J.M; Juste R.A; Fernandez A; González-Recio O; Alonso-Hearn M; (2022)
A Genome-Wide Association Study for Tolerance to Paratuberculosis Identifies Candidate Genes Involved in DNA Packaging;DNA Damage Repair;Innate Immunity;and Pathogen Persistence
Frontiers in Immunology
DOI: 10.3389/fimmu.2022.820965
Kleinman-Ruiz D; Lucena-Perez M; Villanueva B; Fernández J; Saveljev A.P; Ratkiewicz M; Schmidt K; Galtier N; García-Dorado A; Godoy J.A; (2022)
Purging of deleterious burden in the endangered Iberian lynx
Proceedings of the National Academy of Sciences of the United States of America
DOI: 10.1073/pnas.2110614119
Caballero, A., Fernández, A., Villanueva, B., Toro, M.A. (2022)
A comparison of marker-based estimators of inbreeding and inbreeding depression
Genetics Selection Evolution | 54
DOI: 10.1186/s12711-022-00772-0
Fernández J, Villanueva B, Toro MA (2021)
Optimum mating designs for exploiting dominance in genomic selection schemes for aquaculture species
Genetics Selection Evolution | 53
DOI: 10.1186/s12711-021-00610-9
Villanueva, B, Fernández, A, Saura, M, Caballero, A, Fernandez, J, Morales-González, E, Toro, MA, Pong-Wong, R (2021)
The value of genomic relationship matrices for estimating inbreeding
Genetics Selection Evolution | 53
DOI: 10.1186/s12711-021-00635-0
Morales-González, E, Fernández, J, Pong-Wong, R, Toro, MA, Villanueva, B. (2021)
Changes in allele frequencies when different genomic coancestry matrices are used for maintaining genetic diversity
Genes | 12
DOI: 10.3390/genes12050673
Diz AP, Romero MR, Galindo J, Saura M, Skibinski DOF, Rolán-Álvarez E. (2021)
Proteomic analysis of F1 hybrids and intermediate variants in a Littorina saxatilis hybrid zone
Current Zoology
DOI: 10.1093/cz/zoab054
García-Ballesteros S, Fernández J, Toro MA, Villanueva B. (2021)
Benefits of genomic evaluation in aquaculture breeding programs with separate rearing of families
Aquaculture | 543
DOI: 10.1016/j.aquaculture.2021.737004
García-Ballesteros S, Villanueva B, Fernández J, Gutiérrez JP, Cervantes I. (2021)
Genetic parameters for uniformity of harvest weight in Pacific white shrimp (Litopenaeus vannamei)
Genetics Selection Evolution | 53
DOI: 10.1186/s12711-021-00621-6
Saura, M., Caballero, A., Santiago, E., Fernández, A., Morales-González, E., Fernández, J., Cabaleiro, S., Millán, A., Martínez, P., Palaiokostas, C., Kocour, M., Aslam, L., Houston, R.D., Prchal, M., Bargelloni, L., Kostas, T., Bruant, J.S., Haffray, P., Villanueva, B. (2021)
Estimates of recent and historical effective population size in turbot, seabream, seabass and carp selective breeding programmes
Genetics Selection Evolution | 53
DOI: 10.1186/s12711-021-00680-9
Mínguez J.J; El Bouyafrouri Y; Godoy J.A; Rivas A; Fernández J; Asensio V; Serra R; Perez-Aspa M.J; Lorenzo V; (2021)
Benign juvenile idiopathic epilepsy in captive Iberian lynx (Lynx pardinus) in the ex situ conservation program (2005–2019)
BMC Veterinary Research
DOI: 10.1186/s12917-021-02868-z
Rodríguez-Ramilo, S.T., Reverter, A., Sánchez, J.P., Fernández, J., Velasco-Galilea, M., González, O., Piles, M. (2020)
Networks of inbreeding coefficients in a selected population of rabbits
Journal of Animal Breeding and Genetics | 137 : 599-608
DOI: 10.1111/jbg.12500
Toro, M.A., Villanueva, B., Fernández, J. (2020)
The concept of effective population size loses its meaning in the context of optimal management of diversity using molecular markers
Journal of Animal Breeding and Genetics | 137 : 345-355
DOI: 10.1111/jbg.12455
Morales-González, E., Saura, M., Fernández, A., Fernández, J., Pong-Wong, R., Cabaleiro, S., Martínez, P., Martín-García, A., Villanueva, B. (2020)
Evaluating different genomic coancestry matrices for managing genetic variability in turbot
Aquaculture | 520
DOI: 10.1016/j.aquaculture.2020.734985
Caballero, A., Villanueva, B., Druet, T. (2020)
On the estimation of inbreeding depression using different measures of inbreeding from molecular markers
Evolutionary Applications | 14 : 1-13
DOI: 10.1111/eva.13126
Gicquel, E., Boettcher, P., Besbes, B., Furre, S., Fernández, J., Danchin-Burge, C., Berger, B., Baumung, R., Feijoó, J.R.J., Leroy, G. (2020)
Impact of conservation measures on demography and genetic variability of livestock breeds
Animal | 14 : 670-680
DOI: 10.1017/S1751731119002672
Leroy, G, Gicquel, E, Boettcher, P, Besbes, B, Furre, S, Fernandez, J, Danchin-Burge, C, Nabeel, A, Baumung, R (2020)
Coancestry rate's estimate of effective population size for genetic variability monitoring
Conservation Genetic Resources | 12 : 275-283
DOI: 10.1007/s12686-019-01092-0
Anacleto, O., Cabaleiro, S., Villanueva, B., Saura, M., Houston, R.D., Woolliams, J.A., Doeschl-Wilson, A.B. (2019)
Genetic differences in host infectivity affect disease spread and survival in epidemics
Scientific Reports | 9
DOI: 10.1038/s41598-019-40567-w
Kleinman-Ruiz, D., Soriano, L., Casas-Marce, M., Szychta, C., Sánchez, I., Fernández, J., Godoy, J.A. (2019)
Genetic evaluation of the Iberian lynx ex situ conservation programme
Heredity | 123 : 647-661
DOI: 10.1038/s41437-019-0217-z
Gabián, M., Morán, P., Fernández, A.I., Villanueva, B., Chtioui, A., Kent, M.P., Covelo-Soto, L., Fernández, A., Saura, M. (2019)
Identification of genomic regions regulating sex determination in Atlantic salmon using high density SNP data
BMC Genomics | 20
DOI: 10.1186/s12864-019-6104-4
López-Cortegano, E., Pouso, R., Labrador, A., Pérez-Figueroa, A., Fernández, J., Caballero, A. (2019)
Optimal Management of Genetic Diversity in Subdivided Populations
Frontiers in Genetics | 10
DOI: 10.3389/fgene.2019.00843
Saura M, Carabaño MJ, Fernández A, Cabaleiro S, Doeschl-Wilson AB, Anacleto O, Maroso F, Millán A, Hermida M, Fernández C, Martínez P, Villanueva B. (2019)
Disentangling genetic variation for resistance and endurance to scuticulociliatosis in turbot using pedigree and genomic information
Frontiers in Genetics | 10
DOI: 10.3389/fgene.2019.00539
Solé, M, Valera, M, Sánchez, MJ. Azor, P.J, Fernández, J (2019)
Drawbacks and consequences of selective strategies in the design of semen banks: case study of the Pura Raza Español horse breed
Livestock Science | 226 : 93-98
DOI: 10.1016/j.livsci.2019.06.010
Godoy JA, Rodríguez A, Palomares F, Fernández J, Revilla E, Delibes M. (2019)
Declive y recuperación del lince ibérico: el papel de la investigación
Recuperando biodiversidad. La contribución del CSIC para evitar la extinción de especies. Ed: M. Ferrer. CSIC. ISBN: 978-84-00-10542-6
DOI:
Amorim, S.T., Kluska, S., Berton, M.P., de Lemos, M.V.A., Peripolli, E., Stafuzza, N.B., Martin, J.F., Álvarez, M.S., Gaviña, B.V., Toro, M.A., Banchero, G., Oliveira, P.S., Grigoletto, L., Eler, J.P., Baldi, F., Ferraz, J.B.S. (2018)
Genomic study for maternal related traits in Santa Inês sheep breed
Livestock Science | 217 : 76-84
DOI: 10.1016/j.livsci.2018.09.011
Sciara, A.A., Rodríguez-Ramilo, S.T., Hermida, M., Gómez-Tato, A., Fernández, J., Bouza, C., Martínez, P. (2018)
Validation of growth-related quantitative trait loci markers in turbot (Scophthalmus maximus) families as a step toward marker assisted selection
Aquaculture | 495 : 602-610
DOI: 10.1016/j.aquaculture.2018.06.010
Solé, M, Valera, M, Fernandez, J (2018)
Genetic structure and connectivity analysis in a large domestic livestock meta-population: The case of the Pura Raza Español horses
Journal of Animal Breeding and Genetics | 135 : 460-471
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Maroso F, Hermida M, Millán A, Blanco A, Saura M, Fernández A, Dalla Rovere M, Bargelloni L, Cabaleiro S, Villanueva B, Bouza C, Martínez P. (2018)
Highly dense linkage maps from 31 full-sibling families of turbot (Scophthalmus maximus) provide insights into recombination patterns and chromosome rearrangements throughout a newly refined genome assembly
DNA Research | 25 : 439-450
DOI: 10.1093/dnares/dsy015
Rivas MJ, Saura M, Pérez-Figueroa A, Panova M, Johansson T, André C, Caballero A, Rolán-Álvarez A, Quesada H. (2018)
Population genomics of parallel evolution in gene expression and gene sequence during ecological adaptation
Scientific Reports | 8
DOI: 10.1038/s41598-018-33897-8
Kleinman-Ruiz, D., Martínez-Cruz, B., Soriano, L., Lucena-Perez, M., Cruz, F., Villanueva, B., Fernández, J., Godoy, J.A. (2017)
Novel efficient genome-wide SNP panels for the conservation of the highly endangered Iberian lynx
BMC Genomics | 18
DOI: 10.1186/s12864-017-3946-5
Toro, M.A., Saura, M., Fernandez, J., Villanueva, B. (2017)
Accuracy of genomic within-family selection in aquaculture breeding programmes
Journal of Animal Breeding and Genetics | 134 : 256-263
DOI: 10.1111/jbg.12272
Saura, M., Villanueva, B., Fernández, J., Toro, M.A. (2017)
Effect of assortative mating on genetic gain and inbreeding in aquaculture selective breeding programs
Aquaculture | 472 : 30-37
DOI: 10.1016/j.aquaculture.2016.05.013
Velando, A., Morán, P., Romero, R., Fernández, J., Piorno, V. (2017)
Invasion and eradication of the American mink in the Atlantic Islands National Park (NW Spain): a retrospective analysis
Biological Invasions | 19 : 1227-1241
DOI: 10.1007/s10530-016-1326-8
Fernandes, T., Herlin, M., Belluga, M.D.L., Ballón, G., Martinez, P., Toro, M.A., Fernández, J. (2017)
Estimation of genetic parameters for growth traits in a hatchery population of gilthead seabream (Sparus auratus L.)
Aquaculture International | 25 : 499-514
DOI: 10.1007/s10499-016-0046-5
Berton MP, Silva RMO, Peripolli E, Stafuzza NB, Fernández J, Saura M, Villanueva B, Toro MA, Banchero G Oliveira PS, Eler JP, Baldi F, Ferraz JBS (2017)
Genomic regions and pathways associated with resistance to gastrointestinal parasites in Santa Inês breed adapted to the tropical climate
Journal of Animal Science and Biotechnology | 8
DOI: 10.1186/s40104-017-0190-4
García-Ballesteros S, Gutiérrez JP, Varona L, Fernández J. (2017)
The influence of natural selection in breeding programs: A simulation study
Livestock Science | 204 : 98-103
DOI: 10.1016/j.livsci.2017.08.017
Martínez P, Bouza C, Fernández J. (2017)
Introduction to genetics in aquaculture XII
Aquaculture | 472 : 2-3
DOI: 10.1016/j.aquaculture.2017.05.040
Fernandez J, Bennewitz J. (2017)
Defining genetic diversity based on genomic tools
Genomic management of animal genetic diversity. Ed: K. Oldenbroek. Wageningen Academic Publishers. ISBN: 978-90-8686-297-9
DOI:
Gómez-Romano, F., Villanueva, B., Sölkner, J., de Cara, M.A., Mészáros, G., Pérez O'Brien, A.M., Fernández, J. (2016)
The use of coancestry based on shared segments for maintaining genetic diversity
Journal of Animal Breeding and Genetics | 133 : 357-365
DOI: 10.1111/jbg.12213
Tirado, T., Saura, M., Rolán-Alvarez, E., Quesada, H. (2016)
Historical biogeography of the marine snail littorina saxatilis inferred from haplotype and shell morphology evolution in NW Spain
PLoS ONE | 11
DOI: 10.1371/journal.pone.0161287
Kleinman-Ruiz, D., Villanueva, B., Fernández, J., Toro, M.A., García-Cortés, L.A., Rodríguez-Ramilo, S.T. (2016)
Intra-chromosomal estimates of inbreeding and coancestry in the Spanish Holstein cattle population
Livestock Science | 185 : 34-42
DOI: 10.1016/j.livsci.2016.01.002
Fernández, J., Toro, M.A., Gómez-Romano, F., Villanueva, B. (2016)
The use of genomic information can enhance the efficiency of conservation programs
Animal Frontiers | 6 : 59-64
DOI: 10.2527/af.2016-0009
Gómez-Romano, F., Villanueva, B., Fernández, J., Woolliams, J.A., Pong-Wong, R. (2016)
The use of genomic coancestry matrices in the optimisation of contributions to maintain genetic diversity at specific regions of the genome
Genetics Selection Evolution | 48
DOI: 10.1186/s12711-015-0172-y
Martínez P, Robledo D, Rodríguez-Ramilo ST, Hermida M, Taboada X, Pereiro P, Rubiolo JA, Ribas L, Gómez-Tato A, Álvarez-Dios JA, Piferrer F, Novoa B, Figueras A, Pardo B, Fernández J, Viñas A, Bouza C. (2016)
Turbot (Scophthalmus maximus) genomic resources: application for boosting aquaculture production
Genomics in aquaculture. Eds: S. A. MacKenzie, S. Jentoft. Academic Press, Elsevier. ISBN: 978-01-2801-418-9 | 131-163
DOI: 10.1016/B978-0-12-801418-9.00006-8
Saura, M., Fernández, A., Varona, L., Fernández, A.I., De Cara, M.Á.R., Barragán, C., Villanueva, B. (2015)
Detecting inbreeding depression for reproductive traits in Iberian pigs using genome-wide data
Genetics Selection Evolution | 47
DOI: 10.1186/s12711-014-0081-5
Saura, M., Tenesa, A., Woolliams, J.A., Fernández, A., Villanueva, B. (2015)
Evaluation of the linkage-disequilibrium method for the estimation of effective population size when generations overlap: An empirical case
BMC Genomics | 16
DOI: 10.1186/s12864-015-2167-z
Covelo-Soto, L., Saura, M., Morán, P. (2015)
Does DNA methylation regulate metamorphosis? The case of the sea lamprey (Petromyzon marinus) as an example
Comparative Biochemistry and Physiology Part - B: Biochemistry and Molecular Biology | 185 : 42-46
DOI: 10.1016/j.cbpb.2015.03.007
Rodríguez-Ramilo, S.T., Fernández, J., Toro, M.A., Hernández, D., Villanueva, B. (2015)
Genome-Wide estimates of coancestry, inbreeding and effective population size in the spanish holstein population
PLoS ONE | 10
DOI: 10.1371/journal.pone.0124157
Rodríguez-Ramilo, S.T., De La Herrán, R., Ruiz-Rejón, C., Hermida, M., Fernández, C., Pereiro, P., Figueras, A., Bouza, C., Toro, M.A., Martínez, P., Fernández, J. (2014)
Identification of Quantitative Trait Loci Associated with Resistance to Viral Haemorrhagic Septicaemia (VHS) in Turbot (Scophthalmus maximus): A Comparison Between Bacterium, Parasite and Virus Diseases
Marine Biotechnology | 16 : 265-276
DOI: 10.1007/s10126-013-9544-x
Lhorente, J.P., Gallardo, J.A., Villanueva, B., Carabaño, M.J., Neira, R. (2014)
Disease resistance in atlantic salmon (Salmo salar): Coinfection of the intracellular bacterial pathogen piscirickettsia salmonis and the sea louse caligus rogercresseyi
PLoS ONE | 9
DOI: 10.1371/journal.pone.0095397.t001
Galindo, J., Rivas, M.J., Saura, M., Rolán-Alvarez, E. (2014)
Selection on hybrids of ecologically divergent ecotypes of a marine snail: The relative importance of exogenous and endogenous barriers
Biological Journal of the Linnean Society | 111 : 391-400
DOI: 10.1111/bij.12197
Fernández, A.I., Barragán, C., Fernández, A., Rodríguez, M.C., Villanueva, B. (2014)
Copy number variants in a highly inbred Iberian porcine strain
Animal Genetics | 45 : 357-366
DOI: 10.1111/age.12137
Toro, M.A., Villanueva, B., Fernández, J. (2014)
Genomics applied to management strategies in conservation programmes
Livestock Science | 166 : 48-53
DOI: 10.1016/j.livsci.2014.04.020
Fernández, J., Toro, M.Á., Sonesson, A.K., Villanueva, B. (2014)
Optimizing the creation of base populations for aquaculture breeding programs using phenotypic and genomic data and its consequences on genetic progress
Frontiers in Genetics | 5
DOI: 10.3389/fgene.2014.00414
Cros, D., Sánchez, L., Cochard, B., Samper, P., Denis, M., Bouvet, J.-M., Fernández, J. (2014)
Estimation of genealogical coancestry in plant species using a pedigree reconstruction algorithm and application to an oil palm breeding population
Theoretical and Applied Genetics | 127 : 981-994
DOI: 10.1007/s00122-014-2273-3
Butlin, R.K., Saura, M., Charrier, G., Jackson, B., André, C., Caballero, A., Coyne, J.A., Galindo, J., Grahame, J.W., Hollander, J., Kemppainen, P., Martínez-Fernández, M., Panova, M., Quesada, H., Johannesson, K., Rolán-Alvarez, E. (2014)
Parallel evolution of local adaptation and reproductive isolation in the face of gene flow
Evolution | 68 : 935-949
DOI: 10.1111/evo.12329
Rodríguez-Ramilo, ST, Toro, MA, Wang, J, Fernández, J (2014)
Improving the inference of population genetic structure in presence of related individuals
Genetics Research | 96
DOI: 10.1017/S0016672314000068
Hermida M, Rodríguez-Ramilo ST, Hachero-Cruzado I, Herrera M, Sciara A, Bouza C, Fernández J, Martínez P. (2014)
First genetic linkage map for comparative mapping and QTL screening of brill (Scophthalmus rhombus)
Aquaculture | 420-421
DOI: 10.1016/j.aquaculture.2013.02.041
Mastrangelo, S., Saura, M., Tolone, M., Salces-Ortiz, J., Di Gerlando, R., Bertolini, F., Fontanesi, L., Sardina, M.T., Serrano, M., Portolano, B. (2014)
The genome-wide structure of two economically important indigenous sicilian cattle breeds
Journal of Animal Science | 92 : 4833-4842
DOI: 10.2527/jas.2014-7898
De Cara, M.A.R., Villanueva, B., Toro, M.A., Fernández, J. (2013)
Using genomic tools to maintain diversity and fitness in conservation programmes
Molecular Ecology | 22 : 6091-6099
DOI: 10.1111/mec.12560
Ávila, V., Vilas, A., Fernández, J., Caballero, A. (2013)
An experimental assessment of artificial within-family selection for fitness in conservation programs
Conservation Genetics | 14 : 1149-1159
DOI: 10.1007/s10592-013-0502-y
Saura, M., Fernandez, A., Rodriguez, M.C., Toro, M.A., Barragan, C., Fernandez, A.I., Villanueva, B. (2013)
Genome-wide estimates of coancestry and inbreeding in a closed herd of ancient iberian pigs
PLoS ONE | 8
DOI: 10.1371/journal.pone.0078314
Gómez-Romano, F., Villanueva, B., Rodríguez De Cara, M.A., Fernández, J. (2013)
Maintaining genetic diversity using molecular coancestry: The effect of marker density and effective population size
Genetics Selection Evolution | 45
DOI: 10.1186/1297-9686-45-38
Silió, L., Rodríguez, M.C., Fernández, A., Barragán, C., Benítez, R., Óvilo, C., Fernández, A.I. (2013)
Measuring inbreeding and inbreeding depression on pig growth from pedigree or SNP-derived metrics
Journal of Animal Breeding and Genetics | 130 : 349-360
DOI: 10.1111/jbg.12031
Sánchez-Molano, E., Caballero, A., Fernández, J. (2013)
Efficiency of conservation management methods for subdivided populations under local adaptation
Journal of Heredity | 104 : 554-564
DOI: 10.1093/jhered/est016
Solé, M., Valera, M., Gómez, M.D., Cervantes, I., Fernández, J. (2013)
Implementation of Optimum Contributions Selection in endangered local breeds: The case of the Menorca Horse population
Journal of Animal Breeding and Genetics | 130 : 218-226
DOI: 10.1111/jbg.12023
Amador, C., Fernández, J., Meuwissen, T.H.E. (2013)
Advantages of using molecular coancestry in the removal of introgressed genetic material
Genetics Selection Evolution | 45
DOI: 10.1186/1297-9686-45-13
de Cara, MAR, Villanueva, B, Toro, MA, Fernández, J (2013)
Purging deleterious mutations in conservation programmes: combining optimal contributions with inbred matings
Heredity | 110 : 530-537
DOI: 10.1038/hdy.2012.119
Hermida M, Bouza C, Fernández C, Sciara A, Rodríguez-Ramilo ST, Fernández J, Martínez P. (2013)
Compilation of mapping resources in turbot (Scophthalmus maximus): A new integrated consensus genetic map
Aquaculture | 414 : 19-25
DOI: 10.1016/j.aquaculture.2013.07.040
Novel P, Porta J, Fernández J, Méndez T, Gallardo-Gálvez JB, Béjar J, Alvarez MC. (2013)
Critical points for the maintenance of genetic variability over a production cycle in the European sea bass, Dicentrarchus labrax
Aquaculture | 414 : 8-14
DOI: 10.1016/j.aquaculture.2013.08.005
Rodríguez-Ramilo ST, Fernández J, Toro MA, Bouza C, Hermida M, Fernández C, Pardo BG, Cabaleiro S, Martínez P. (2013)
Uncovering QTL for resistance and survival time to Philasterides dicentrarchi in turbot (Scophthalmus maximus)
Animal Genetics | 44 : 149-157
DOI: 10.1111/j.1365-2052.2012.02385.x
Seno, L.O., Fernández, J., Cardoso, V.L., García-Cortes, L.A., Toro, M., Santos, D.O., Albuquerque, L.G., de Camargo, G.M.F., Tonhati, H. (2012)
Selection strategies for dairy buffaloes: Economic and genetic consequences
Journal of Animal Breeding and Genetics | 129 : 488-500
DOI: 10.1111/j.1439-0388.2012.00992.x
Doeschl-Wilson, A.B., Bishop, S.C., Kyriazakis, I., Villanueva, B. (2012)
Novel methods for quantifying individual host response to infectious pathogens for genetic analyses
Frontiers in Genetics | 3
DOI: 10.3389/fgene.2012.00266
Amador, C., Toro, M.Á., Fernández, J. (2012)
Molecular Markers Allow to Remove Introgressed Genetic Background: A Simulation Study
PLoS ONE | 7
DOI: 10.1371/journal.pone.0049409
García-Casco, J.M., Fernández, A., Rodríguez, M.C., Silió, L. (2012)
Heterosis for litter size and growth in crosses of four strains of Iberian pig
Livestock Science | 147 : 1-8
DOI: 10.1016/j.livsci.2012.03.005
Doeschl-Wilson AB, Villanueva B, Kyriazakis I. (2012)
The first step toward genetic selection for host tolerance to infectious pathogens: Obtaining the tolerance phenotype through group estimates
Frontiers in Genetics | 3
DOI: 10.3389/fgene.2012.00265
Fernández J, Clemente I, Amador C, Membrillo A, Azor P, Molina A. (2012)
Use of different sources of information for the recovery and genetic management of endangered populations: Example with the extreme case of Iberian pig Dorado strain
Livestock Science | 149 : 282-288
DOI: 10.1016/j.livsci.2012.07.019
Lhorente JP, Gallardo JA, Villanueva B, Araya AM, Torrealba DA, Toledo XE, Neira R. (2012)
Quantitative genetic basis for resistance to Caligus rogercresseyi sea lice in a breeding population of Atlantic salmon (Salmo salar)
Aquaculture | 324 : 55-59
DOI: 10.1016/j.aquaculture.2011.10.046
Rolán-Álvarez E, Saura M, Diz AP, Rivas MJ, Álvarez M, Cortés B, de Coo A, Estévez D, Iglesias L. (2012)
Can sexual selection and disassortative mating contribute to the maintenance of a shell color polymorphism in an intertidal marine snail?
Current Zoology | 58 : 463-474
DOI: 10.1093/czoolo/58.3.463
Saura M, Rivas MJ, Diz AP, Caballero A, Rolán-Álvarez E. (2012)
Dietary effects on shell growth and shape in an intertidal marine snail, Littorina saxatilis
Journal of Molluscan Studies | 78 : 213-216
DOI: 10.1093/mollus/eys004
González-Recio O.; López-Catalina A.; Peiró-Pastor R.; Nieto-Valle A.; Castro M.; Fernández A; (1899)
Evaluating the potential of (epi)genotype-by-low pass nanopore sequencing in dairy cattle: a study on direct genomic value and methylation analysis
Journal of Animal Science and Biotechnology
DOI: 10.1186/s40104-023-00896-3
Gonzalez-Recio O.; Scrobota N.; López-Paredes J.; Saborío-Montero A.; Fernández A.; López de Maturana E.; Villanueva B.; Goiri I.; Atxaerandio R.; García-Rodríguez A; (1899)
Review: Diving into the cow hologenome to reduce methane emissions and increase sustainability
Animal
DOI: 10.1016/j.animal.2023.100780

Jesús Fernández
Carrying out the genetic management of a selection programme in the population of Penaeus vannamei in Nicaragua - Bajamar Séptima, Sociedad Anónima (Grupo Pescanova)
2015 - 2016 |
Jesús Fernández
Carrying out the genetic management of a selection programme in the population of Penaeus vannamei in Ecuador - Bajamar Séptima, Sociedad Anónima (Grupo Pescanova)
2015 - 2016 |
Jesús Fernández
Design and development of a genetic selection plan to improve production in sole (Solea senagalensis) - Safiestela S.A.
2015 - 2016 | CON15-179
Jesús Fernández
Implementation and management of genetic selection of the shrimp breeding programme of the National Aquaculture Group
2020 - 2023 | NAQUA
Jesús Fernández
Management and analysis of diversity in structured populations in the fields of conservation of genetic resources and animal breeding: Theoretical studies - MICINN
2010 - 2012 | CGL2009-13278-C02-02
Beatriz Villanueva
Use of genomic tools for the conservation of the Iberian pig - MICINN
2010 - 2014 | RZ2010-00009-00-00
Jesús Fernández
Genetic selection programme to improve the production of seabream and seabass at the ABSA S.A.U.
2011 - 2013 | CDTI
Beatriz Villanueva
Productive characterization and conservation in Uruguayan Creole sheep - FAO
2013 - 2015 | CI14-023
Beatriz Villanueva
Estimation of the impact of selection and inbreeding on genetic diversity using genomic tools: Applications in animal breeding and conservation - MINECO
2013 - 2015 | CGL2012-39861-C02-02
Jesús Fernández
Biotechnological advances in the reproduction, genetics and health of sole - CDTI
2015 - 2018 | IDI-20150906
María Saura
Optimal design of the Galician Atlantic salmon conservation programme using genomic tools - MINECO
2013 - 2016 | RZ2012-00011-C02
Jesús Fernández
Genetic selection programme for the improvement of growth in seabream (Sparus aurata, L.); evaluation of genetic progress achieved
2014 - 2017 | CDTI
Beatriz Villanueva
Improving European aquaculture by advancing selective breeding to the next level for the six main finfish species - Unión Europea (FP7)
2014 - 2019 | FISHBOOST
Jesús Fernández
Analysis and control of molecular inbreeding and coancestry in the management of genetic resources for conservation and animal breeding - MINECO
2017 - 2020 | CGL2016-75904-C2-2
Beatriz Villanueva
Mediterranean Aquaculture Integrated Development - Unión Europea (H2020)
2017 - 2021 | MedAID
María Saura
Estimation of the impact of the host inbreeding on the genetic diversity and abundance of microbiota of ovine reproductive tracts
2019 - 2022 | RTI2018-096487-R-C33
Beatriz Villanueva
Estimation of effective size and inbreeding depression using genomic data: applications in animal breeding - MICINN
2021 - 2025 | PID2020-114426GB-C22

Silvia García-Ballesteros García
Optimisation of aquaculture improvement programmes, using genomic tools (in progress)
Dirección: Universidad Complutense de Madrid
Elisabeth Morales González
Analysis and control of genomic coancestry for the management of genetic resources in conservation and genetic improvement programmes (in progress)
Dirección: Universidad Politécnica de Valencia
Edgar L Reinoso Peláez
Study of the metagenome of the reproductive tracts and determination of its role in the reproductive efficiency of the ovine species (in progress)
Dirección: Universidad Politécnica de Madrid
Daniel Kleinman Ruiz
From genetics to genomics in the conservation of the Iberian lynx (2020)
Dirección: Universidad de Sevilla
Tiago Fernandes
Optimisation of selection programmes in aquaculture (2020)
Dirección: Universidad de Cádiz
Fernando Gómez Romano
Managing genetic diversity in conservation programmes using high density marker panels (2015)
Dirección: Universidad Complutense de Madrid
Lara Covelo
Role of DNA methylation in the control of development and genomic stability in two anadromous fish species (Petromyzus marinus y Salmo trutta) (2015)
Dirección: Universidad de Vigo
Carmen Amador Arranz
Population management strategies to reverse exogenous gene introgression (2012)
Dirección: Universidad Complutense de Madrid
Jean Paul Lhorente
Evaluation of specific and joint genetic resistance to pathogens Caligus rogercresseyi and Piscirickettsia salmonis in Atlantic salmon (2012)
Dirección: Universidad de Chile